Christina Applegate has learned she does not have multiple sclerosis after being incorrectly diagnosed five years ago, leaving her upset and facing further medical investigation into her worsening symptoms.
01Summary
- 01Applegate revealed the wrong diagnosis on her Messy podcast, released Tuesday.
- 02She stopped MS infusion treatment on her doctor's advice and her body did not respond as expected.
- 03Doctors concluded she does not have the autoimmune disease, which can cause muscle stiffness and walking difficulties.
- 04Research suggests 15 to 20 percent of MS patients may be misdiagnosed, according to Dr Elena Grebenciucova.
- 05Dr Philip De Jager, director of the Multiple Sclerosis Center at Columbia University, recommends patients seek second opinions.
02Why it matters
This story highlights the emotional and physical toll of a chronic illness misdiagnosis, and underscores the importance of seeking second opinions for conditions like MS that lack a definitive test.
Answers are generated by AI from the story summary; they are not investment, health or legal advice.





